For some reason, the OpenEmu interface does not currently have a button to reset the controller settings.
Editing the gamepad settings, I accidentally overlaid something. But the simpler option is to reset the settings (key bindings) in OpenEmu.
Searching the network did not give a better result than deleting the OpenEmu controller configuration file (after starting the emulator, it will generate a new file with default settings).
So here. The file must be deleted Default.oebindings
The file is here:
~/Library/Application\ Support/OpenEmu/Bindings
Deleting a file using a terminal: