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What is the ALEX test and what does it include?

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ALEX test or ALEX² test (Allergy Explorer) — is a modern molecular allergy test performed on a blood sample that allows for the detection of sensitization to 295 allergens simultaneously.

What does the ALEX test determine?

  • Total IgE level — immunoglobulin E, responsible for allergic reactions.
  • Specific IgE to:
    • Molecular components of allergens (e.g., individual proteins in pollen, foods, etc.),
    • Whole extracts of allergens (e.g., birch pollen, milk, dust mites, etc.).

Advantages of the ALEX² test:

  • Minimum blood (only a few microliters),
  • One test instead of dozens of separate analyses,
  • Detection of cross-allergy (e.g., between pollen and fruits),
  • Can be done even while taking antihistamines,
  • Painless (does not cause an allergic reaction, unlike skin tests),
  • Creation of an allergy profile or patient passport.

What is it needed for?

  • Diagnosis of respiratory, food, contact allergies,
  • Understanding which specific molecules cause allergies (this is important for deciding whether to conduct allergen-specific immunotherapy),
  • Detection of hidden or non-obvious allergens.
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What exactly is included in the ALEX test?

Grass pollen:
  • Cynodon dactylon
  • Medicago sativa
  • Paspalum
  • Phleum pratense
  • Common reed
  • Rye
Tree pollen:
  • Silver acacia (genus of tropical trees)
  • Ailanthus altissima
  • Black alder (sticky)
  • Downy birch
  • Paper mulberry
  • Hazel
  • Cryptomeria japonica
  • Arizona cypress
  • Evergreen cypress
  • Ash (high)
  • Walnut
  • Mexican juniper (mountain cedar)
  • Red mulberry
  • Date palm
  • Platanus acerifolia
  • Black poplar (aspen)
  • Elm
Weed pollen:
  • Amaranth
  • Ambrosia artemisiifolia
  • Common wormwood
  • Common hemp
  • White goosefoot
  • Annual bluegrass
  • Wall lettuce
  • Lanceolate plantain
  • Curly dock
  • Nettle
House dust mites and storage mites:
  • Acarus siro
  • American house dust mite
  • Blomia tropicalis
  • European house dust mite
  • Glycyphagus domesticus
  • Lepidoglyphus destructor
  • Tyrophagus putrescentiae
Legumes:
  • Chickpea
  • White bean
  • Lentil
  • Pea
  • Peanut
  • Soybean
Cereals: 
  • Barley
  • Buckwheat
  • Corn
  • Rye
  • Lupin
  • Millet
  • Oats
  • Quinoa
  • Rice
  • Wheat
Spices:
  • Anise
  • Cumin
  • Mustard
  • Oregano
  • Paprika
  • Parsley
Fruits:
  • Avocado
  • Apple
  • Banana
  • Blueberry
  • Cherry
  • Fig
  • Grape
  • Kiwi
  • Mango
  • Melon
  • Orange
  • Papaya
  • Peach
  • Pear
  • Strawberry
Vegetables:
  • Carrot
  • Celery
  • Garlic
  • Onion
  • Potato
  • Tomato
Nuts and seeds:
  • Almond
  • Brazil nut
  • Cashew
  • Hazelnut
  • Macadamia
  • Pecan
  • Pistachio
  • Walnut
  • Fenugreek seeds
  • Poppy
  • Pumpkin seeds
  • Sesame
  • Sunflower seeds
Roach:
  • American cockroach
  • German cockroach
Insect venom:
  • Common wasp venom
  • Fire ant venom
  • Honeybee venom
  • Paper wasp venom
  • Long-headed wasp venom
Mold and yeast fungi:
  • Alternaria alternata
  • Aspergillus fumigatus
  • Baker's yeast
  • Cladosporium herbarum
  • Malassezia sympodialis
  • Penicillium chrysogenum
Milk:
  • Camel milk
  • Cow's milk
  • Goat's milk
  • Horse milk
  • Sheep milk
Egg:
  • Egg white
  • Egg yolk
Fish and seafood:
  • Anisakis
  • Atlantic cod
  • Atlantic herring
  • Atlantic mackerel
  • Black tiger shrimp
  • Common shrimp
  • Carp
  • Common mussel
  • Crab
  • Lobster
  • North shrimp
  • Oyster
  • Salmon
  • Scallop
  • Shrimp mix
  • Squid
  • Swordfish
  • Sea fox
  • Tuna
  • Venereids
Meat of domestic animals and insects:
  • Beef
  • Chicken
  • Horse meat
  • Lamb
  • Pork
  • Rabbit
  • Turkey
  • House cricket
  • Migratory locust
  • Flour beetle
Pets:
  • Cat
  • Dzungarian hamster
  • Dog
  • Guinea pig
  • Mouse
  • Rabbit
  • Rat
Livestock:
  • Cattle
  • Goat
  • Horse
  • Pig
  • Sheep
Others:
  • Latex
  • Hom s lactoferrin
  • Bird mite
  • Ficus

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